SPIM 2026

Skin Physiology International Meeting

Conceive and show new research ways
in the dermocosmetology field

November 19th & 20th, 2026, Vichy FRANCE

PLANNING AND TOPICS

SPIM 2026 - 10thedition

LONGEVITY & HEALTHY SKIN

Nov. 19th, 2026

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Dr Jean-Marc LEMAÎTRE, Research Director INSERM, Institute of Regenerative Medicine Montpellier

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Dr Maria CAVINATO, Institute for Biomedical Aging Research, University of Innsbruck

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Prof. Carmit LEVY, School of Medicine, 1026, Tel-Aviv University

physiological benefit of UV exposure other than vitamin D production

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Dr Anita KRISKO, Aion Research, Goettingen, Germany

Proteostasis, respiration and metabolism: a ménage-a-trois of cellular longevity View more

In cells living under optimal conditions, as well as during stress and aging, protein folding defects are usually prevented by the action of chaperones.

Here, we will discuss a new perspective in which cellular proteostasis, including chaperone activity and protein aggregation, is implicated in basic cellular functioning via its previously unknown crosstalk with metabolism and mitochondrial function. We propose that protein maintenance machineries are not only managers of client misfolded proteins, but also act as key determinants of cellular metabolic activity, thereby representing the main axis of cellular quality control and a central homeostatic mechanism relevant to cellular health and longevity.

These findings populate an important niche in cell biology as well as longevity and diseases, promising the possibility of replacing the need for interventions in the chaperone expression levels by treatment with a single or a group of metabolites. Understanding this crosstalk will enable novel insights into basic cellular functioning, and may shed new light on the process of aging, and neurodegenerative diseases.
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MICROBIOTA & EPITHELIAL BARRIER

Nov. 20th, 2026,

9.00 – 12.30

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Dr Ellen Van Den BOGAARD, Radboud University

Various roles of AHR in epidermal function

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Prof. Julia OH, The Jackson Laboratory, US

The human skin microbiome: microbial modulation of skin homeostasis View more

The human skin harbors an abundant microbial ecosystem with bidirectional metabolic exchanges supporting symbiotic and commensal functions. Metagenomic analyses of the diverse skin sites in healthy humans demonstrate that contrasting forces of the skin’s biogeography and individual characteristics shape the skin microbiome and the dynamics of its bacteria, fungi, and viruses. However, we have shown that shifts in the ecological properties of the skin microbiome are significantly associated with aging, skin disease, disease severity, and monogenic skin and immune disorders. We have used a variety of computational and functional approaches, including metagenomics, CRISPRi screening, organoid platforms, transcriptomic and spatial transcriptomics, and other technologies to probe genetic and functional diversity of the skin microbiome.
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Prof. Joël DORÉ, Paris-Saclay University

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Dr Cédric DELEVOYE, Research Director, INSERM U1151/CNRS 8253

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Pr Marc G.J. FEUILLOLEY, Emeritus Professor, University of Rouen Normandy

Endocrine Microbiology, from gut to skin

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PROGRAM TO BE CONFIRMED

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The Greentech awards

State of the art in skin physiology

In its will to promote knowledge on skin physiology, and to encourage younger generation of scientists to search further, the Fondation d’Entreprise GREENTECH, organizer of the SPIM – will grant an award to 2 participants in the following categories.

Junior Scientist Award: €10,000

6 junior scientists will be selected and invited by the scientific committee for an oral presentation of their research. Travel and accommodation will be supported by the Committee.

For paper submission guidelines, click here

Best Poster Award: €3,000

All participants, whether they are junior researchers or not, have the opportunity to present a poster related to research on skin physiology. The winning poster will be selected through a vote involving all SPIM participants.

For paper submission guidelines, click here

What is the SPIM?

State of the art in skin physiology

The SPIM is a unique scientific meeting at the crossroads of research excellence and international conviviality. Putting latest research work and discoveries on skin physiology at its center, the event aims at sharing and mixing thoughts, views and investigation methods between various disciplines without dogmatic position.

It involves experts from all specialisations (physiologists, biochemists, dermatologists and pharmacologists) and all countries (USA, Great Britain, Germany, Italy, Japan, France, etc) and encourages cross-collaboration to push further scientific understanding of skin physiology and metabolic interactions, for both healthy and disorder skin states.

Each SPIM has been and is designed in collaboration with our scientific committee gathering renowned Scientists and Physicians with large experience in the area of skin physiology, dermatology and cosmetology.